Handbook of Pharmaceutical Excipients 7 Updated Ed

Handbook of Pharmaceutical Excipients 7 Updated EdBook Reviews: Pharmaceutical dosage forms contain both pharmacologically active compounds and excipients added to aid the formulation and manufacture of the subsequent dosage form for administration to patients. Indeed, the properties of the final dosage form (i.e. its bioavailability and stability) are, for the most part, highly dependent on the excipients chosen, their concentration and interaction with both the active compound and each other. No longer can excipients be regarded simply as inert or inactive ingredients, and a detailed knowledge not only of the physical and chemical properties but also of the safety, handling and regulatory status of these materials is essential for formulators throughout the world. In addition, the growth of novel forms of delivery has resulted in an increase in the number of the excipients being used and suppliers of excipients have developed novel excipient mixtures and new physical forms to improve their properties. The Handbook of Pharmaceutical Excipients has been conceived as a systematic, comprehensive resource of information on all of these topics.

Arrangement:

The information consists of monographs that are divided into 22 sections to enable the reader to find the information of interest easily. Although it was originally intended that each monograph contain only information about a single excipient, it rapidly became clear that some substances or groups of substances should be discussed together. This gave rise to such monographs as ‘Coloring Agents’ and ‘Hydrocarbons’. In addition, some materials have more than one monograph depending on the physical characteristics of the material, e.g. Starch versus Pregelatinized Starch. Regardless of the complexity of the monograph they are all divided into 22 sections as follows:

1. Nonproprietary Names

2. Synonyms

3. Chemical Name and CAS Registry Number

4. Empirical Formula and Molecular Weight

5. Structural Formula

6. Functional Category

7. Applications in Pharmaceutical Formulation or

Technology

8. Description

9. Pharmacopeial Specifications

10. Typical Properties

11. Stability and Storage Conditions

12. Incompatibilities

13. Method of Manufacture

14. Safety

15. Handling Precautions

16. Regulatory Status

17. Related Substances

18. Comments

19. Specific References

20. General References

21. Authors

22. Date of Revision

Bibliographical Data of Handbook of Pharmaceutical Excipients 7 Updated Ed

Reference Type: Book
Record Number: XX
Author: Raymond C. Rowe
Year: 2012
Place Published: London, UK
Publisher: Pharmaceutical Press
Number of Pages: 1064
Edition: 7
ISBN -10: 0857110276
ISBN-13: 978-0857110275
Buy: Get it on Amazon

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